Which of the following accounts for someone who has had a herpesvirus-mediated cold sore or genital sore getting flare-ups for the rest of his or her life?
A) re-infection by a closely related herpesvirus of a different strain
B) re-infection by the same herpesvirus strain
C) co-infection with an unrelated virus that causes the same symptoms
D) copies of the herpesvirus genome permanently maintained in host nuclei
E) copies of the herpesvirus genome permanently maintained in host cell cytoplasm

Question

Quizplus · Accepted Answer

Once a herpesvirus infects a host, it establishes a life-long latent infection by inserting its genetic material into the DNA of the host cells, where it remains indefinitely. Under certain triggers, such as stress or a weakened immune system, the virus can reactivate and lead to recurrent symptoms. Therefore, the correct answer is copies of the herpesvirus genome permanently maintained in the host nuclei (D).

Which of the Following Accounts for Someone Who Has Had