A geneticist introduces a transgene into yeast cells and isolates five independent cell lines in which the transgene has integrated into the yeast genome. In four of the lines, the transgene is expressed strongly, but in the fifth there is no expression at all.
-Of the lines that express the transgene, one is transcribed but not translated. Which of the following is a likely explanation?
A) no promoter
B) no AUG in any frame
C) no compatible ribosome
D) high histone acetylation
E) missing transcription factor

Question

Quizplus · Accepted Answer

If there is no AUG in any frame, then translation cannot occur, which would explain why transcription is happening but no protein is being produced.

A Geneticist Introduces a Transgene into Yeast Cells and Isolates