What would be the effect on primordial germ cells when an embryo is exposed to laminin-specific neutralizing antibodies?
A)They arrive at the developing gonad more quickly.
B)Their movement to the developing gonad is disrupted.
C)They begin to divide rapidly.
D)They increase greatly in size.
E)Their nuclei disintegrate.

Question

Quizplus · Accepted Answer

Laminin is an extracellular matrix protein that is important for cell migration and adhesion. Primordial germ cells (PGCs) migrate from the hindgut to the developing gonad during early embryonic development, and this migration process is dependent on the interaction between laminin and integrin receptors on the surface of PGCs. Exposure to laminin-specific neutralizing antibodies would disrupt this interaction and prevent PGCs from migrating properly, resulting in a decrease or delay in their arrival at the developing gonad. Therefore, the effect on PGCs would be a disruption of their movement to the developing gonad.

What Would Be the Effect on Primordial Germ Cells When