What is usually the retrieval signal for escaped ER membrane proteins?
A)KKXX at the C-terminus of the protein
B)KDEL at the C-terminus of the protein
C)KDEL at the N-terminus of the protein
D)KKXX at the N-terminus of the protein
E)KXEL at the C-terminus of the protein

Question

Quizplus · Accepted Answer

The retrieval signal for escaped ER membrane proteins is KDEL at the C-terminus of the protein. This signal is recognized by the KDEL receptor, which retrieves escaped ER proteins from the Golgi and returns them to the ER.

What Is Usually the Retrieval Signal for Escaped ER Membrane