Which method of repair can be slower, less efficient, and responsible for correcting DNA strands in the parts of the genome that are not being currently transcribed?
A)transcription-coupled pathway of NER
B)global genomic pathway of NER
C)base excision repair
D)replicative repair

Question

Quizplus · Accepted Answer

The global genomic pathway of NER can be slower, less efficient, and responsible for correcting DNA strands in the parts of the genome that are not being currently transcribed, as compared to the transcription-coupled pathway of NER which is specifically responsible for correcting DNA damage within actively transcribed genes, and is therefore more efficient and quicker. Base excision repair and replicative repair are different types of DNA repair mechanisms and are not directly comparable to the two NER pathways. Therefore, option B is the best choice.

Which Method of Repair Can Be Slower, Less Efficient, and Responsible