The hydrolysis of ATP to ADP has a △G°^ʹof -30 kJ/mol. If in an E. coli cell the concentrations of ATP, ADP and inorganic phosphate are 7.90 mM, 1.04 mM and 7.9 mM, respectively, which statement is true about the hydrolysis of ATP in the cell? Assume a temperature of 298 K. R = 8.315 J/K-mol) A) Hydrolysis can proceed spontaneously. B) The hydrolysis is at equilibrium. C) The formation of ATP from ADP is occurring more rapidly than the hydrolysis. D) The hydrolysis is being allosterically controlled.

Question

Quizplus · Accepted Answer

The hydrolysis of ATP to ADP has a △G°^ʹof -30 kJ/mol. This means that the reaction is exergonic and can proceed spontaneously. The concentrations of ATP, ADP and inorganic phosphate in the cell are 7.90 mM, 1.04 mM and 7.9 mM, respectively. The reaction quotient (Q) is calculated as follows:Q = [ADP][Pi]/[ATP] = (1.04 mM)(7.9 mM)/(7.90 mM) = 1.05The equilibrium constant (K) is calculated as follows:K = exp(-△G°^ʹ/RT) = exp(-(-30 kJ/mol)/(8.315 J/K-mol)(298 K)) = 1.05Since Q = K, the reaction is at equilibrium.

The Hydrolysis of ATP to ADP Has a △G°ʹ of

The Hydrolysis of ATP to ADP Has a △G°^ʹof