Define codon bias. If synonymous substitutions give the same amino acid, why should there be a bias in which codons are used to encode that amino acid?

Name: Define codon bias. If synonymous substitutions give the same amino acid, why should there be a bias in which codons are used to encode that amino acid?
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The Answer of Define codon bias. If synonymous substitutions give the same amino acid, why should there be a bias in which codons are used to encode that amino acid?

Define Codon Bias