What is required for DNA polymerase to initiate DNA strand synthesis?
A) a short DNA primer synthesized by the enzyme primase
B) a short RNA primer synthesized by the enzyme primase
C) ATP and a short RNA primer synthesized by the enzyme topoisomerase
D) ATP and a short DNA primer synthesized by the enzyme topoisomerase
E) DNA polymerase initiates DNA strand synthesis without requiring any additional enzymes.

Question

Quizplus · Accepted Answer

DNA polymerase requires a short RNA primer synthesized by the enzyme primase to initiate DNA strand synthesis. This RNA primer provides a free 3' hydroxyl group for the addition of DNA nucleotides.

What Is Required for DNA Polymerase to Initiate DNA Strand