The signal recognition peptide
A) Binds to the signal sequence and to the SRP receptor
B) Binds to the signal sequence and to the translocon
C) Binds to the SRP and to the translocon
D) Binds to the signal sequence inside the ER lumen
E) Helps fold up proteins inside the ER

Question

Quizplus · Accepted Answer

The signal recognition peptide (SRP) plays a crucial role in targeting proteins to the endoplasmic reticulum (ER) membrane by binding to the signal sequence of the nascent polypeptide as it emerges from the ribosome and subsequently interacting with the SRP receptor on the ER membrane. This interaction facilitates the transfer of the ribosome-nascent chain complex to the translocon for protein translocation into the ER.

The Signal Recognition Peptide