In general, negative charges on proteins
A) Increases their sieving coefficient towards 1.0
B) Inhibits filtration because of negatively charged solutes in the ultrafiltrate
C) Reduces filtration because of negative charges in the basement membrane and slit
diaphragm
D) Has no effect on filtration at the glomerulus
E) Enhances filtration due to positive charges in the basement membrane and slit diaphragm

Question

Quizplus · Accepted Answer

Negative charges on proteins reduce filtration because the basement membrane and slit diaphragm of the glomerulus also carry negative charges. This electrostatic repulsion inhibits the passage of negatively charged molecules, affecting their filtration.

In General, Negative Charges on Proteins