Which of the Following Helped to Destabilize the Ottoman Empire

Which of the following helped to destabilize the Ottoman Empire during the seventeenth century?

A) Mughal invaders took over large amounts of Ottoman territory in the eastern part of the empire.
B) The Ottomans lacked the initiative to make needed administrative reforms.
C) The Ottoman population was declining due to diseases from the Americas, leaving it too weak to resist foreign encroachment.
D) Military campaigns and a growing population strained the empire's resources.