Cholera toxin polypeptide A binds to surface gangliosides on target cells. If the gangliosides were removed,
A) polypeptide A would enter the cells.
B) Vibrio would bind to target cells.
C) Vibrio would not produce cholera toxin.
D) polypeptide A would bind to target cells.
E) polypeptide B would not be able to enter the cells.

Question

Quizplus · Accepted Answer

Gangliosides are necessary for the binding and entry of cholera toxin subunits into the cells. Without them, polypeptide B, which is part of the cholera toxin, would not be able to enter the cells.

Cholera Toxin Polypeptide a Binds to Surface Gangliosides on Target