Which one of the following would you predict is an allosteric inhibitor of the Krebs cycle enzyme, α-ketoglutarate dehydrogenase?
A) ADP
B) α-ketoglutaric acid
C) NAD+
D) NADH
E) citric acid

Question

Quizplus · Accepted Answer

NADH is an allosteric inhibitor of α-ketoglutarate dehydrogenase, as high levels of NADH indicate sufficient energy supply, signaling the enzyme to slow down the Krebs cycle.

Which One of the Following Would You Predict Is an Allosteric