Which of the following would be suggested by a DNase hypersensitive site?
A) No transcription occurs in this region of the chromosome.
B) The chromatin is in an open state and available for transcription.
C) Transcription terminates at this site.
D) It indicates a region devoid of (lacking)genes.
E) The DNA is highly methylated.

Question

Quizplus · Accepted Answer

A DNase hypersensitive site (DHS) is a region of chromatin that is more accessible to cleavage by the enzyme DNase I than the surrounding chromatin. This suggests that the chromatin in this region is in an open state and available for transcription. DHSs are often found near regulatory elements such as enhancers and promoters, indicating their importance in regulating gene expression.

Which of the Following Would Be Suggested by a DNase