Intercalating agents such as ethidium bromide function as mutagens to
A) promote transitions.
B) remove amine groups.
C) attach to purines causing distortions.
D) add ethyl or methyl groups.
E) fit between stacked bases and disrupt replication.

Question

Quizplus · Accepted Answer

Intercalating agents like ethidium bromide insert themselves between the stacked bases of the DNA helix, causing physical distortions. This disruption can lead to mutations during DNA replication or transcription because the DNA polymerase may insert incorrect bases opposite the intercalated molecule, leading to frameshift mutations.

Intercalating Agents Such as Ethidium Bromide Function as Mutagens to