The switch of one B cell from producing one class of antibody to another class of antibody that is responsive to the same antigen is due to ________.
A) the rearrangement of V region genes in that clone of responsive B cells
B) a switch in the kind of antigen-presenting cell that is involved in the immune response
C) a patient's reaction to the first kind of antibody made by the plasma cells
D) the rearrangement of immunoglobulin heavy-chain C region DNA

Question

Quizplus · Accepted Answer

The switch of one B cell from producing one class of antibody to another class of antibody that is responsive to the same antigen is due to the rearrangement of immunoglobulin heavy-chain C region DNA. This process is known as class switching and results in the production of a different antibody class, while maintaining the same antigen specificity as the original antibody.

The Switch of One B Cell from Producing One Class