Why do the cells of the digestive system secrete proteolytic enzymes, such as pepsin, in their inactive forms?
A) These proteolytic enzymes, in active form, would digest the very tissues that synthesize them.
B) By secreting inactive enzymes, the catalytic activity of the enzymes is maintained for a longer time.
C) The stomach is too acidic to maintain these enzymes in their active form.
D) Inactive pepsin and trypsin are more easily transported across the cell membrane

Question

Quizplus · Accepted Answer

If proteolytic enzymes such as pepsin were secreted in their active form, they would begin to digest the cells that synthesize them, resulting in self-digestion of the digestive system. Therefore, it is necessary for the cells to secrete these enzymes in their inactive forms and activate them only when needed.

Why Do the Cells of the Digestive System Secrete Proteolytic