Suppose that a researcher is successful at producing induced pluripotent stem cells (iPS) for replacement of pancreatic insulin-producing cells for people with type 1 diabetes. Which of the following could still pose problems for this individual?
I.the possibility that, once introduced into the patient, the iPS cells produce non-pancreatic cells
II.the failure of the iPS cells to take up residence in the pancreas
III.the inability of the iPS cells to respond to appropriate regulatory signals
A) I only
B) II only
C) III only
D) I, II, and III

Question

Quizplus · Accepted Answer

All of the listed possibilities could pose problems for the effectiveness of the iPS cells in replacing pancreatic insulin-producing cells for people with type 1 diabetes. If the iPS cells produce non-pancreatic cells, they will not be able to fulfill their intended function. If the iPS cells do not take up residence in the pancreas, they will not be able to function in the appropriate tissue microenvironment. Additionally, if the iPS cells are unable to respond to regulatory signals, their function could be impaired. Therefore, all of these possibilities need to be addressed in order to ensure the success of iPS cell therapy for type 1 diabetes.

Suppose That a Researcher Is Successful at Producing Induced Pluripotent