The most commonly occurring mutation in people with cystic fibrosis is a deletion of a single codon. What is the result of this type of mutation?
A) a base-pair substitution
B) a frameshift mutation
C) a polypeptide missing an amino acid
D) a nonsense mutation

Question

Quizplus · Accepted Answer

The deletion of a single codon results in the loss of one amino acid in the polypeptide chain, which is characteristic of the most common mutation in cystic fibrosis, known as the ΔF508 mutation.

The Most Commonly Occurring Mutation in People with Cystic Fibrosis