Which of the following processes is the first event to take place in translation in eukaryotes?
A) base pairing of activated methionine-tRNA to AUG of the messenger RNA
B) binding of the larger ribosomal subunit to smaller ribosomal subunits
C) the ribosome reaches a stop codon
D) the small subunit of the ribosome recognizes and attaches to the 5′ cap of mRNA

Question

Quizplus · Accepted Answer

In eukaryotes, the first event to take place in translation is the recognition and attachment of the small subunit of the ribosome to the 5' cap of mRNA. This allows for the ribosome to scan the mRNA for the start codon (AUG) and initiate translation. Base pairing of activated methionine-tRNA to AUG of the mRNA and binding of the larger ribosomal subunit to smaller ribosomal subunits occur later in the process. The ribosome reaching a stop codon marks the end of translation.

Which of the Following Processes Is the First Event to Take