Increased testosterone levels reduce the secretion of gonadotropin-releasing hormone from the anterior pituitary. This is an example of
A) inhibition of hormone release by humoral stimuli.
B) inhibition of hormone release by neural stimuli.
C) inhibition of hormone release by external stimuli.
D) inhibition of hormonal release by environmental stimuli.
E) inhibition of hormone release by hormonal stimuli.

Question

Quizplus · Accepted Answer

Increased testosterone levels reducing the secretion of gonadotropin-releasing hormone (GnRH) is an example of a feedback loop where the hormone (testosterone) itself inhibits further hormone release (GnRH from the hypothalamus, not the anterior pituitary as mentioned in the question, which is a mistake). This is known as hormonal or endocrine feedback, specifically negative feedback, where the product of a pathway inhibits its own further production or secretion.

Increased Testosterone Levels Reduce the Secretion of Gonadotropin-Releasing Hormone from the Anterior