In some forms of diabetes, an insensitivity to insulin seems to be present. This insensitivity could be the result of ________.
A) up-regulation
B) over-regulation
C) down-regulation
D) a lack of regulation
E) modulation

Question

Quizplus · Accepted Answer

Down-regulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external variable. In the context of insulin insensitivity, down-regulation refers to the decrease in the number of insulin receptors on the surface of cells. This reduction in insulin receptors can lead to a decreased response to insulin, a hallmark of type 2 diabetes.

In Some Forms of Diabetes, an Insensitivity to Insulin Seems