Which Statement About Prescription Opioids Is Accurate

Which statement about prescription opioids is accurate?

A) Research indicates more males than females are addicted to prescription opioids, and many turn to criminal activities to support their drug habit.
B) Research indicates dependency to prescription opioids rarely interferes with the dependent person's ability to maintain relationships and a career.
C) Research indicates tolerance to prescription opioids builds up very gradually and withdrawal effects are slight or nonexistent.
D) Research indicates many opioid-abusers began their habit with prescribed opioids, eventually buying prescription opioids illegally or trying heroin.