Which property of antibodies is the basis for complement fixation tests?
A) The Fc portion of IgG becomes enzymatically active upon antigen binding.
B) The Fc portion can trigger the classical complement system upon antigen binding.
C) Antibodies can bind two antigens simultaneously.
D) The Fc portion of the molecule can be modified without interfering with antigen binding.
E) Antibodies can neutralize the ability of viruses to infect cells.

Question

Quizplus · Accepted Answer

The complement fixation test is based on the ability of the Fc portion of antibodies, particularly IgG and IgM, to activate the classical complement pathway upon binding to an antigen.

Which Property of Antibodies Is the Basis for Complement Fixation