A ʺmini-geneʺ has the base sequence TACCCGTGCACG. If the T at the beginning of the sequence is deleted, what will be the consequence?
A) RNA polymerase will correct the deletion, and a normal protein will be produced.
B) The first nucleotide is always replaced anyway, so there will be no change.
C) RNA polymerase will skip that codon, but all the others will be read normally.
D) Only the amino acid coded for in that codon will be changed.
E) All of the codons after that point will be changed.

Question

Quizplus · Accepted Answer

Deleting the first nucleotide (T) from the sequence causes a frameshift mutation, altering the reading frame for all subsequent codons, which changes the amino acids they encode.

A ʺMini-Geneʺ Has the Base Sequence TACCCGTGCACG