The insect hormone ecdysone is known to trigger apoptosis during metamorphosis that turns larva into adult structures. Which of the following experiments would confirm the activation of apoptosis by ecdysone?
A) Inhibition of rpg and hid gene via RNAi should result in excess cells that would normally be eliminated.
B) Overproduction of rpg and hid genes via constitutive promoter should prevent the full metamorphosis.
C) Inhibition of receptor binding to ecdysone should result in excess apoptosis.
D) Overproduction of ecdysone receptor should result in inhibition of rpg and hid genes.
E) Inactivation of grim should result in elimination of excess number of cells.

Question

Quizplus · Accepted Answer

Inhibition of rpg and hid genes, which are pro-apoptotic, should result in excess cells that would normally be eliminated through apoptosis, confirming that ecdysone triggers apoptosis.

The Insect Hormone Ecdysone Is Known to Trigger Apoptosis During