The results of linkage analysis for DNA marker A and the p53 gene are shown below. What is the best estimate for the approximate genetic distance between marker A and the p53 gene in humans? $$\begin{array} { c c c c c c c }
\text { Recombination values (m.u.) } & 1 & 5 & 10 & 20 & 30 & 40 \
\text { lod score } & 2.13 & 2.54 & 3.14 & 4.10 & 4.96 & 3.22
\end{array}$$
A) 1 m.u.
B) 5 m.u.
C) 10 m.u.
D) 20 m.u.
E) 30 m.u.

Question

The results of linkage analysis for DNA marker A and the p53 gene are shown below. What is the best estimate for the approximate genetic distance between marker A and the p53 gene in humans? $$\begin{array} { c c c c c c c } 
\text { Recombination values (m.u.) } & 1 & 5 & 10 & 20 & 30 & 40 \
\text { lod score } & 2.13 & 2.54 & 3.14 & 4.10 & 4.96 & 3.22
\end{array}$$
A) 1 m.u.
B) 5 m.u.
C) 10 m.u.
D) 20 m.u.
E) 30 m.u.

Quizplus · Accepted Answer

The highest lod score is 4.96 at 30 m.u., indicating the most likely genetic distance between marker A and the p53 gene.

The Results of Linkage Analysis for DNA Marker a and the P53