What is the likely consequence of a mutation that alters the branch point within an intron?
A)no effect, since introns are not expressed
B)failure to form a lariat
C)failure of snRNPs to recognize the 5' end of intron
D)no exon shuffling

Question

Quizplus · Accepted Answer

Failure to form a lariat is the likely consequence of a mutation that alters the branch point within an intron. The branch point is a specific sequence within the intron that is recognized by the spliceosome, a complex of proteins and RNA molecules that removes introns from pre-mRNA. If the branch point is mutated, the spliceosome will not be able to recognize it, and the intron will not be removed from the pre-mRNA. This will result in a mature mRNA that contains the intron, which will prevent the mRNA from being translated into protein.

What Is the Likely Consequence of a Mutation That Alters