How does inactive MLH1 contribute to the development of some forms of inherited colon cancer?
A) It results in the deletion of a nucleotide repeat in the DUX4 gene.
B) DNA damage is left unrepaired.
C) There is an expansion in the number of cytosine-guanine (CG) dinucleotide.
D) Downregulation of IGF2 occurs.

Question

Quizplus · Accepted Answer

Inactive MLH1 leads to a failure in the DNA mismatch repair system, resulting in DNA damage being left unrepaired, which can contribute to the development of inherited colon cancer.

How Does Inactive MLH1 Contribute to the Development of Some