Which can result in Down syndrome? (Select all that apply. )
A)nondisjunction resulting in an extra chromosome 21
B)a reciprocal translocation between acrocentric chromosomes 14 and 21
C)deletions of a segment of chromosome 21
D)having the triploid number of chromosomes

Question

Quizplus · Accepted Answer

Down syndrome is most commonly caused by nondisjunction leading to an extra chromosome 21 (trisomy 21). It can also result from a Robertsonian translocation involving chromosome 21, such as a translocation between chromosomes 14 and 21. Deletions of chromosome 21 or triploidy do not typically result in Down syndrome.

Which Can Result in Down Syndrome? (Select All That Apply