Fragile X syndrome is a human disease caused by a trinucleotide repeat expansion that results in loss-of-function of the FMR1 gene on the X chromosome.An animal model with most features of this syndrome could be created by
A)adding a transgene containing a mutant copy of the FMR1 gene to a mouse or primate genome.
B)adding a transgene containing a wild-type copy of the FMR1 gene to a mouse or primate genome.
C)knocking out both copies of the FMR1 gene from a mouse or primate genome.
D)knocking out one copy of the FMR1 gene from a mouse or primate genome.

Question

Quizplus · Accepted Answer

Knocking out both copies of the FMR1 gene would mimic the loss-of-function seen in Fragile X syndrome, creating an animal model with similar features.

Fragile X Syndrome Is a Human Disease Caused by a Trinucleotide