What type of protein is PTEN,which is mutated in 50% of prostate cancers?
A)kinase
B)phosphatase
C)growth factor receptor
D)G protein
E)ubiquitin ligase

Question

Quizplus · Accepted Answer

PTEN is a phosphatase, specifically a dual-specificity phosphatase, that plays a critical role in regulating cell growth by dephosphorylating phosphatidylinositol 3,4,5-trisphosphate (PIP3) and thus negatively regulating the PI3K/AKT signaling pathway. Its mutation or loss of function is associated with various cancers, including a significant percentage of prostate cancers.

What Type of Protein Is PTEN,which Is Mutated in 50