Each of the following statements regarding CD95-stimulated programmed cell death is true except
A)CD95 ligand binding with CD95 receptor stimulates recruitment of adaptor proteins.
B)adaptor proteins stimulate the PI3K-Akt pathway.
C)recruitment to sites of receptor clustering activates initiator caspase (caspase 8)activity.
D)initiator caspases proteolytically cleave executioner procaspases (procaspase 3).
E)a caspase cascade results in the cleavage of many types of proteins in the target cell.

Question

Quizplus · Accepted Answer

The PI3K-Akt pathway is generally associated with cell survival and proliferation, not with the promotion of apoptosis. In the context of CD95-stimulated programmed cell death, adaptor proteins facilitate the activation of caspases, leading to apoptosis rather than stimulating the PI3K-Akt survival pathway.

Each of the Following Statements Regarding CD95-Stimulated Programmed Cell Death