What would most likely trigger the peripheral chemoreceptors when uncontrolled diabetes is present? A) excessive H+ accumulation B) low PaCO₂ C) low H+ levels in the blood D) high PaCO₂

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Peripheral chemoreceptors are sensitive to changes in the partial pressure of oxygen, carbon dioxide, and the pH of blood and cerebrospinal fluid. In the case of uncontrolled diabetes, the body cannot properly use glucose for energy, leading to the breakdown of fats for energy, which produces ketones. The accumulation of ketones in the blood can lead to ketoacidosis, a condition characterized by excessive H+ accumulation (acidosis), which would trigger the peripheral chemoreceptors.

What Would Most Likely Trigger the Peripheral Chemoreceptors When Uncontrolled