Some tumor cells have a large number of Cl^- channels on the plasma membrane. This makes the Cl^-permeability higher than that of any other ion and therefore: A) Causes the cell to swell when suspended in isotonic NaCl B) Causes the cell to shrink when suspended in isotonic NaCl C) Increases the steady state intracellular osmolality D) Decreases the steady state intracellular osmolality E) Causes the membrane potential to be near the equilibrium potential for Cl^-

Question

Quizplus · Accepted Answer

The high Cl^- permeability means that the membrane potential is likely to be close to the equilibrium potential for Cl^-, as the ion with the highest permeability has the greatest influence on the membrane potential.

Some Tumor Cells Have a Large Number of Cl- Channels

Some Tumor Cells Have a Large Number of Cl^- Channels