Many inherited disorders result from defective alleles.Which of the following genetic combinations is most likely to result in a disorder such as sickle-cell anemia?
A)Recessive,defective alleles from both parents
B)A defective,recessive allele from the mother
C)A defective,recessive allele from the father
D)One normal allele and one recessive allele from each parent

Question

Quizplus · Accepted Answer

Sickle-cell anemia is caused by a recessive, defective allele. If a person inherits one defective allele and one normal allele, they are carriers of the disorder but typically do not show symptoms. However, if they inherit two defective alleles (one from each parent), then they will develop sickle-cell anemia.

Many Inherited Disorders Result from Defective Alleles