The majority of the neurotransmitter norepinephrine (NE)is metabolized in the synaptic cleft.

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The majority of the neurotransmitter norepinephrine (NE) is actually taken back up by the presynaptic neuron through a process known as reuptake, where it can be reused or metabolized within the neuron. Only a small percentage of NE is metabolized in the synaptic cleft by enzymes such as monoamine oxidase (MAO).

The Majority of the Neurotransmitter Norepinephrine (NE)is Metabolized in the Synaptic