Codeine is metabolized to morphine via the hepatic enzyme:
A) CYP-3A4.
B) CYP-2D6.
C) CYP-2P6.
D) CYP-3D4.

Name: Codeine is metabolized to morphine via the hepatic enzyme: A) CYP-3A4. B) CYP-2D6. C) CYP-2P6. D) CYP-3D4.
Brand: Quizplus
Rating: 4.9 (36 reviews)

Question

Quizplus · Accepted Answer

Codeine is primarily metabolized to morphine by the hepatic enzyme CYP-2D6. People who are poor metabolizers of CYP-2D6 may experience decreased analgesic effects and increased adverse effects of codeine due to reduced conversion to morphine.

Codeine Is Metabolized to Morphine Via the Hepatic Enzyme