After 5 months of taking nortriptyline (Aventyl) for depressive symptoms, a client reports that the medication doesn't seem as effective as before. Which question should the nurse ask to determine the cause of this problem?

Question

Quizplus · Accepted Answer

Nortriptyline is metabolized by the liver enzyme CYP2D6, and smoking can induce this enzyme, leading to increased metabolism of the drug and potentially reducing its effectiveness. Asking about smoking habits can help determine if this is the cause of the decreased efficacy.

After 5 Months of Taking Nortriptyline (Aventyl) for Depressive Symptoms