Progression through the M phase checkpoint is stimulated by a complex that does which of the following things?
A)activates separase to cleave cohesin proteins
B)activates separase to modify kinetochores
C)activates motor molecules at the centromere to begin disassembly of spindle microtubules
D)activates assembly of spindle microtubules

Question

Quizplus · Accepted Answer

The M phase checkpoint ensures that chromosomes have properly aligned on the metaphase plate before moving into anaphase. The complex responsible for progression through this checkpoint activates separase, an enzyme that cleaves cohesin proteins that hold sister chromatids together. This allows the chromatids to separate and move towards opposite poles of the cell during anaphase.

Progression Through the M Phase Checkpoint Is Stimulated by a Complex