Which of the Following Environments Would Most Likely Lead to the Transcription

Which of the following environments would most likely lead to the transcription of the lactose operon?

A) There is more glucose in the cell than lactose.
B) The cyclic AMP levels are low.
C) There is glucose but no lactose in the cell.
D) The cyclic AMP and lactose levels are both high within the cell.
E) The cAMP level is high and the lactose level is low.