Which of the following statements most correctly describes the whole-genome shotgun approach for sequencing a genome?
A)genetic mapping followed immediately by sequencing
B)physical mapping followed immediately by sequencing
C)cloning fragments from many copies of an entire chromosome,sequencing the fragments,and then ordering the sequences
D)cloning the whole genome directly,from one end to the other

Question

Quizplus · Accepted Answer

The whole-genome shotgun approach involves cloning fragments from many copies of an entire chromosome, sequencing the fragments, and then ordering the sequences to reconstruct the entire genome. This approach does not involve genetic or physical mapping and does not clone the entire genome directly from one end to the other.

Which of the Following Statements Most Correctly Describes the Whole-Genome