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Tetraethylammonium (TEA)is a potent neurotoxin that results in death from respiratory failure within 10 to 30 minutes.When a neuron is incubated with TEA,researchers observed that action potentials could be generated,but the membrane potential remained positive and never returned to the resting membrane potential.
-What channel is TEA likely acting on?
A)voltage-gated sodium channels
B)voltage-gated potassium channels
C)sodium potassium pumps
D)chloride channels

Question

Quizplus · Accepted Answer

The fact that action potentials can be generated but the membrane potential never returns to the resting state suggests that TEA is blocking the repolarization phase of the action potential, which is mediated by voltage-gated potassium channels. The positive membrane potential that persists is likely due to the continued influx of sodium ions through voltage-gated sodium channels.

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