On binding of an insulin molecule to the insulin receptor, a conformational change occurs that
A) increases the affinity of a second insulin binding site.
B) causes the dimerization of the receptor.
C) brings the L1 region of the $\beta$ subunit closer to the membrane.
D) stimulates tyrosine autophosphorylation in the $\beta$ subunits.

Question

Quizplus · Accepted Answer

Binding of insulin to its receptor stimulates tyrosine autophosphorylation in the β subunits, which is crucial for downstream signaling.

On Binding of an Insulin Molecule to the Insulin Receptor β\betaβ

On Binding of an Insulin Molecule to the Insulin Receptor $\beta$