What is an advantage of using methicillin compared with penicillin?
A) Penicillin is susceptible to inactivation by mutant transpeptidase enzymes.
B) Methicillin is resistant to $\beta$-lactamase activity.
C) Penicillin does not bind transpeptidase as well as methicillin.
D) Methicillin does not bind transpeptidase.

Question

Quizplus · Accepted Answer

Methicillin is resistant to F1F1F1S1F1F1F10-lactamase activity, which means it is able to withstand enzymatic inactivation by β-lactamase-producing bacteria. This is an advantage compared to penicillin, which is susceptible to inactivation by mutant transpeptidase enzymes.

What Is an Advantage of Using Methicillin Compared with Penicillin β\betaβ

What Is an Advantage of Using Methicillin Compared with Penicillin $\beta$