Which one of the following would you predict is an allosteric inhibitor of the Krebs cycle enzyme, a- ketoglutarate dehydrogenase? A) a- ketoglutaric acid B) ADP C) NADH D) citric acid E) NAD⁺

Question

Quizplus · Accepted Answer

NADH is an allosteric inhibitor of a- ketoglutarate dehydrogenase because it signals that there is already enough energy (in the form of reduced NADH) being produced by the Krebs cycle and therefore slows down the enzyme's activity.

Which One of the Following Would You Predict Is an Allosteric