During DNA replication, DNA polymerase catalyzes the formation of a bond between the ____ group on the 3′ carbon at the end of a DNA strand and the ____ group on a nucleotide's 5′ carbon.
A)phosphate; hydroxyl
B)hydroxyl; phosphate
C)phosphate; sulfur
D)hydroxyl; sulfur
E)sulfur; phosphate

Question

​During DNA replication, DNA polymerase catalyzes the formation of a bond between the ____ group on the 3′ carbon at the end of a DNA strand and the ____ group on a nucleotide's 5′ carbon.
A)​phosphate; hydroxyl
B)​hydroxyl; phosphate
C)​phosphate; sulfur
D)​hydroxyl; sulfur
E)​sulfur; phosphate

Quizplus · Accepted Answer

DNA polymerase catalyzes the formation of a phosphodiester bond between the hydroxyl group (-OH) on the 3′ carbon at the end of a DNA strand and the phosphate group (-PO4) on a nucleotide's 5′ carbon.

​During DNA Replication, DNA Polymerase Catalyzes the Formation of a Bond

During DNA Replication, DNA Polymerase Catalyzes the Formation of a Bond