With respect to histone modifications, which, if any, of the following statements, is true?
A) histone acetylation always means adding an acetyl group to the side chain of a lysine residue.
B) in histone acetylation each lysine of the histone is acetylated.
C) in histone phosphorylation a phosphate group is transferred to the side chain of a serine .
D) in histone methylation it is the DNA that coils around a nucleosome that is methylated, not the histone itself.

Question

Quizplus · Accepted Answer

Histone acetylation involves adding an acetyl group to the side chain of a lysine residue, but not necessarily every lysine in the histone. Histone phosphorylation involves adding a phosphate group to the side chain of a serine, and histone methylation involves adding a methyl group to the histone itself, not the DNA coiled around it.

With Respect to Histone Modifications, Which, If Any, of the Following