The reaction of what nucleophile and substrate is represented by the following transition state?
A)Methanol with 2-bromopropane
B)Methoxide with 2-bromopropane
C)Methoxide with 1-bromopropane
D)Methanol with 1-bromopropane

Question

The reaction of what nucleophile and substrate is represented by the following transition state? 
A)Methanol with 2-bromopropane 
B)Methoxide with 2-bromopropane 
C)Methoxide with 1-bromopropane 
D)Methanol with 1-bromopropane

Quizplus · Accepted Answer

The transition state depicted in the diagram shows a carbon with partial positive charge (delta +) and a leaving group (Br-) leaving from it. This suggests that the substrate is an alkyl halide and the nucleophile attacks the carbon bearing the leaving group. The only option showing a nucleophile attacking a substrate with a leaving group is methoxide with 2-bromopropane, making option B the correct answer.

The Reaction of What Nucleophile and Substrate Is Represented by the Following