You are conducting a genetic screen using Caenorhabditis elegans embryos to isolate mutations affecting anaphase (A).Therefore,you need to look for embryos in which
A)the centromeres do not move toward the poles.
B)the poles do not move apart.
C)the spindle apparatus does not disassemble.
D)sister chromatids are mismatched and therefore fail to separate.

Question

Quizplus · Accepted Answer

Anaphase is the stage in mitosis or meiosis where the sister chromatids separate and move towards the poles of the cell. Therefore, if the centromeres do not move towards the poles (choice A), it indicates a defect specifically in anaphase. If the poles do not move apart (choice B), it could indicate a defect in other stages of mitosis or meiosis such as metaphase or telophase. The spindle apparatus disassembling (choice C) is a normal part of anaphase and should occur, so observing it not happening would not specifically indicate anaphase defects. Sister chromatids being mismatched (choice D) could cause anaphase defects but would not be specific to it.

You Are Conducting a Genetic Screen Using Caenorhabditis Elegans Embryos